MODULATION BY PHOSPHONIUM IONS OF THE ACTIVITY OF MITOTROPIC AGENTS BASED ON THE CHEMILUMINESCENCE OF LUMINOLS

Modulation by Phosphonium Ions of the Activity of Mitotropic Agents Based on the Chemiluminescence of Luminols

Mitochondria-targeting drugs and diagnostics are used in the monitoring and treatment of mitochondrial pathologies.In this respect, a great number of functional compounds have been made mitotropic by covalently attaching the active moiety onto a triphenylphosphonium (TPP) cation.Among these compounds, a number of molecular detectors for reactive ox

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